R. Srivastava

This study identifies SlPAP26b as a key player in tomato's phosphorus starvation response, independent of SlPHR1 and SlPHL1, through transcriptomics and proteomics analysis.

This paper rewires the Csr Network in E. coli to create tunable genetic circuits for post-transcriptional control, achieving three-fold increased mevalonate production.

This study shows RAGE-Ig reduces viral replication and inflammation in multiple SARS-CoV-2 variants using animal models and human cells.

This study develops a humanized DRAG mouse model to test GBM immunotherapy, showing anti-PD-1 antibodies reduce immunosuppressive cells in xenografted tumors.

This study identifies increased exhaustion and senescence markers in NK and T cells of unvaccinated symptomatic COVID-19 patients, correlating with severe disease.

This study develops a prime/pull vaccine using RR2 and CXCL11 to increase tissue-resident CD8+ TRM cells, reducing HSV-2 reactivation and genital herpes severity in guinea pigs.

The paper identifies SNULs, noncoding RNAs that form nucleolar territories on NOR chromosomes and regulate rRNA expression by influencing pre-rRNA sorting and processing.

The paper identifies increased frequencies of HSV-specific memory B cells in asymptomatic individuals and mice, correlated with memory Tfh cells, suggesting their role in protection against recurrent ocular herpes.

The paper identifies dysfunctional senescent HSV-specific CD8+ T cells in symptomatic herpes patients compared to asymptomatic individuals, linking senescence to recurrent herpes susceptibility.

This study investigates age-related immune impairments in mice following HSV-1 infection, finding reduced type-I interferon production and impaired CD8+ T cell function in aged mice.

This study shows that engineered FGF-1 (TTHX1114) reduces HSV-1-induced corneal disease in mice by increasing anti-inflammatory M2 macrophages and decreasing pro-inflammatory M1 macrophages.

This study identifies four SARS-CoV-2 proteins with strong HLA-1 binding and low energy that could serve as subunit vaccine candidates through immuno-informatics analysis.

This study shows that combining ALK7 inhibition with lifestyle or anti-inflammatory interventions leads to sustained weight loss in obese mice, even under high caloric intake.

The paper develops low-cost, paper-based colorimetric assays and a reflectance-based optical reader for early screening of kidney-related disorders using urine samples.

This study identifies IRF8 as a key factor in tumor-associated macrophages (TAMs) that induce T cell exhaustion by presenting cancer antigens, and shows its association with poor patient survival in renal cell carcinoma.

The paper synthesizes and evaluates substituted aryl phenylthiazolyl phenylcarboxamides as PTP-1B inhibitors, identifying compound 38 as a potent inhibitor with in vivo metabolic benefits.

This study investigates how microtubules and membrane tension drive axonal beading, retraction, and atrophy in neurodegenerative conditions through controlled experiments and theoretical analysis.