Author

R. Dandage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:E. coli· 1

Frequent Co-Authors

C. R. Landry· 2 shared K. Chakraborty· 2 shared A. Chaphalkar· 1 shared A. Shukla· 1 shared C. M. Berger· 1 shared D. Shanmugam· 1 shared G. Jayaraj· 1 shared I. Gagnon-Arsenault· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

C. R. Landry

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Author profile →

4 papers

Recent·Most cited

Frequent assembly of chimeric complexes in the protein interaction network of an interspecies yeast hybrid

R. Dandage, C. M. Berger, I. Gagnon-Arsenault, K.-M. Moon, R. G. Stacey, L. J. Foster, C. R. Landry

This study examines protein-protein interactions in a yeast hybrid, finding frequent chimeric complexes with some exceptions due to parental protein incompatibilities.

bioRxiv · Jun 2, 2020Evolutionary Biology

Distinct metabolic states of a cell guide alternate fates of mutational buffering through altered proteostasis

K. Verma, K. Saxena, R. Donaka, A. Chaphalkar, M. K. Rai, A. Shukla, Z. Zaidi, R. Dandage, D. Shanmugam, K. Chakraborty

The paper shows that metabolic states in E. coli influence proteostasis and mutational buffering through metabolite-dependent chaperone assistance, not increased chaperone levels.

bioRxiv · Mar 20, 2020Biochemistry

Paralog dependency indirectly affects the robustness of human cells

R. Dandage, C. R. Landry

The paper examines how paralog dependency affects cellular robustness by analyzing gene loss-of-function in human cell lines using CRISPR-Cas9.

bioRxiv · Aug 27, 2019Evolutionary Biology

Differential Strengths Of Molecular Determinants Guide Environment Specific Mutational Fates

R. Dandage, R. Pandey, G. Jayaraj, K. Chakraborty

The paper uses Deep Mutational Scanning to analyze how environmental factors influence the fitness of single-site mutants in an antibiotic resistance gene, revealing protein stability as a key constraint.

bioRxiv · May 5, 2017Evolutionary Biology