SETD2 regulates the methylation of translation elongation factor eEF1A1 in clear cell renal cell carcinoma
R. Hapke, L. Venton, K. L. Rose, Q. Sheng, A. Reddy, A. Jones, W. K. Rathmell, S. M. Haake
The paper investigates how SETD2 mutations in clear cell renal cell carcinoma affect protein methylation and translation, finding dysregulated translation linked to poor patient outcomes.
bioRxiv · Oct 26, 2020Cancer Biology