ImmunologybioRxivPreprint
PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity
J. E. Bader, M. M. Wolf, M. Z. Madden…·J. C. Rathmell
This study shows obesity induces PD-1 on tumor-associated macrophages, which suppresses anti-tumor immunity by altering metabolic and functional properties of these cells.