Author

R. Jaiswal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Assay:structural biology· 1

Frequent Co-Authors

C. R. Escalante· 2 shared V. Santosh· 2 shared A. Washington· 1 shared B. Braud· 1 shared B. Vandewinkel· 1 shared C. Dierckx· 1 shared E. Henckaerts· 1 shared F. N. Musayev· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

C. R. Escalante

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2 papers

Recent·Most cited

Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting

R. Jaiswal, V. Santosh, B. Braud, A. Washington, C. R. Escalante

The paper reports Cryo-EM structures of AAV2 Rep68 bound to DNA at the AAVS1 integration site, revealing conformational changes and DNA distortion mechanisms during replication.

bioRxiv · Apr 2, 2024Biochemistry

The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.

V. Santosh, F. N. Musayev, R. Jaiswal, F. Zarate-Perez, B. Vandewinkel, C. Dierckx, M. Endicott, K. Sharifi, K. Dryden, E. Henckaerts, C. R. Escalante

This study determines the Cryo-EM structure of AAV2 Rep68 bound to ssDNA, revealing its ability to switch between oligomeric states through conformational changes.

bioRxiv · Jun 2, 2020Biochemistry