Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
S. Fischer, V. T. Trinh, C. Simon, L. M. Weber, I. Forne, A. Nist, G. Bange, F. Abendroth, T. Stiewe, W. Steinchen, R. Liefke, O. Vazquez
The paper develops a peptide inhibitor targeting the Elongin BC dimer, showing reduced cancer cell viability and increased apoptosis by blocking its interaction partners.
bioRxiv · Nov 4, 2022Cancer Biology