Cancer BiologybioRxiv
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
S. Fischer, V. T. Trinh, C. Simon…·O. Vazquez
The paper develops a peptide inhibitor targeting the Elongin BC dimer, showing reduced cancer cell viability and increased apoptosis by blocking its interaction partners.
DOI 10.1016/j.chembiol.2023.05.012