Author

R. Lima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Fasano· 2 shared A. Bertolini· 1 shared A. Fedier· 1 shared A. G. Edlow· 1 shared A. Kaimal· 1 shared A. Llanos-Chea· 1 shared A. Miranda-Ribera· 1 shared B. Bodenmiller· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

A. Fasano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis

R. Coelho, B. Seashore-Ludlow, S. Schutz, F. Christopher Lombardo, E. Moussaud-Lamodiere, R. Casanova, J. Ficek-Pascual, K. Brunhilde Labrosse, M. Hensle, M. Lopez-Nunez, N. Rimmer, A. Fedier, R. Lima, C. Montavon Sartorius, C. Kurzeder, , F. Jacob

This study shows SMAC mimetics overcome apoptotic resistance in ovarian cancer by targeting the MSLN-TNF alpha axis, enhancing cell death and synergizing with chemotherapy.

bioRxiv · Jan 24, 2024 · PreprintCancer Biology

Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Meinsohn, M. Chauvin, S. Fischinger, L. J. Yockey, K. James, R. Lima, L. M. Yonker, A. Fasano, S. Brigida, L. M. Bebell, , A. G. Edlow

The paper investigates sex differences in placental responses to maternal SARS-CoV-2 infection, finding sex-specific changes in interferon genes, Fc-receptor expression, and antibody transfer.

bioRxiv · Mar 29, 2021 · PreprintImmunology

A versatile human intestinal organoid-derived epithelial monolayer model for the study of enteric pathogens

K. P. Nickerson, A. Llanos-Chea, L. Ingano, G. Serena, A. Miranda-Ribera, M. Perlman, R. Lima, M. B. Sztein, A. Fasano, S. Senger, C. S. Faherty

This paper develops a human intestinal organoid-derived epithelial monolayer model to study enteric pathogens and finds distinct infection patterns across different gut regions and bacterial strains.

bioRxiv · Nov 24, 2020Microbiology