IFN-alpha and 5-Aza-2-deoxycytidine enhance the anti-tumor efficacy of a dendritic-cell targeting MIP3alpha-Gp100-Trp2 DNA vaccine by affecting T-cell recruitment and tumor microenvironment gene expression
This paper shows that combining IFN-alpha and 5-Aza-2-deoxycytidine with a MIP3alpha-Gp100-Trp2 DNA vaccine improves anti-tumor efficacy by enhancing T-cell recruitment and altering tumor microenvironment gene expression.
bioRxiv · Jan 26, 2019 · PreprintImmunology