Author

R. P. Meisel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 6 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

K. Adhikari· 3 shared D. Asgari· 2 shared J. H. Son· 2 shared O. Hassan· 2 shared P. J. Delclos· 2 shared V. Sriskantharajah· 2 shared A. A. Oderhowho· 1 shared A. B. Mai· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersEvolutionary Biology

K. Adhikari

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Author profile →

7 papers

Recent·Most cited

The role of uncertainty and negative feedback loops in the evolution of induced immune defenses

D. Asgari, A. J. Stewart, R. P. Meisel

This study develops a mechanistic model of Drosophila immune signaling to show that induced defenses are favored under conditions of bacterial uncertainty and specific proliferation rates.

bioRxiv · Oct 11, 2022Evolutionary Biology

Thermal tolerance and preference are both consistent with the clinal distribution of house fly proto-Y chromosomes

P. J. Delclos, K. Adhikari, O. Hassan, J. E. Cambric, A. G. Matuk, R. I. Presley, J. Tran, V. Sriskantharajah, R. P. Meisel

This study shows that male-determining chromosomes in house flies affect thermal tolerance and preference in a way consistent with their clinal distribution across latitudes.

Evolution Letters · Oct 1, 2021Peer-reviewedEvolutionary Biology

Trans regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly

P. J. Delclos, K. Adhikari, A. B. Mai, O. Hassan, A. A. Oderhowho, V. Sriskantharajah, T. Trinh, R. P. Meisel

The paper identifies a Y-linked gene that regulates odorant binding proteins, affecting male courtship in house flies and demonstrating a molecular mechanism for sexually antagonistic evolution.

bioRxiv · Jun 22, 2021 · PreprintEvolutionary Biology

Gene expression in Lucilia sericata (Diptera: Calliphoridae) larvae exposed to Pseudomonas aeruginosa and Acinetobacter baumanii identifies shared and microbe-specific induction of immune genes

C. H. McKenna, D. Asgari, T. C. Crippen, L. Zheng, R. A. Sherman, J. K. Tomberlin, R. P. Meisel, A. M. Tarone

bioRxiv · Apr 2, 2021Immunology

Temperature-dependent effects of house fly proto-Y chromosomes on gene expression

K. Adhikari, J. H. Son, A. H. Rensink, J. Jaweria, D. Bopp, L. Beukeboom, R. P. Meisel

The paper investigates temperature-dependent gene expression effects of proto-Y chromosomes in house flies, finding few sex-determining gene effects but many other temperature-interacting genes.

bioRxiv · Aug 5, 2020 · PreprintEvolutionary Biology

The maintenance of polygenic sex determination depends on the dominance of fitness effects which are predictive of the role of sexual antagonism

R. P. Meisel

This study uses simulations to show that overdominant fitness effects on proto-Y chromosomes are more likely to maintain polygenic sex determination than dominant, recessive, or additive effects.

bioRxiv · Jul 8, 2020Evolutionary Biology

Gene-level, but not chromosome-wide, divergence between a very young house fly proto-Y chromosome and its homologous proto-X chromosome

J. H. Son, R. P. Meisel

The paper compares sequence and expression divergence between proto-X and proto-Y chromosomes in house flies, finding gene-level divergence rather than chromosome-wide divergence.

bioRxiv · Apr 2, 2020Evolutionary Biology