Fentanyl depression of respiration: comparison with heroin and morphine
R. Hill, R. Santhakumar, W. L. Dewey, E. Kelly, G. Henderson
This study compares how fentanyl, heroin, and morphine depress respiration in mice, finding that fentanyl's rapid onset, increased muscle stiffness, and reduced naloxone reversal contribute to its higher lethality.
bioRxiv · Jun 6, 2019Pharmacology & Toxicology