Author

E. Kelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:flow cytometry· 1

Frequent Co-Authors

B. Chami· 3 shared H. Zoellner· 3 shared G. Henderson· 2 shared M. A. Moore· 2 shared G. Rogers· 1 shared G. W. Lynch· 1 shared J. A. Cornwell· 1 shared J. Cornwell· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

B. Chami

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell-Projection Pumping of Fibroblast Contents into Osteosarcoma SAOS-2 Cells Correlates with Increased SAOS-2 Proliferation and Migration, and also with Altered Morphology

S. Mahadevan, J. A. Cornwell, B. Chami, E. Kelly, H. Zoellner

The paper tracks fluorescence transfer from fibroblasts to SAOS-2 cells and correlates it with changes in SAOS-2 cell morphology, proliferation, and migration.

bioRxiv · Nov 23, 2021 · PreprintCancer Biology

Fentanyl binds to the mu-opioid receptor via the lipid membrane and transmembrane helices

K. J. Sutcliffe, R. A. Corey, S. J. Charlton, R. B. Sessions, G. Henderson, E. Kelly

This study identifies a novel binding mechanism of fentanyl to the mu-opioid receptor involving membrane partitioning and transmembrane helix diffusion, explaining its high potency and resistance to naloxone.

bioRxiv · Feb 4, 2021 · PreprintPharmacology & Toxicology

Potential hydrodynamic cytoplasmic transfer between mammalian cells: Cell-projection pumping

H. Zoellner, N. Paknejad, J. Cornwell, B. Chami, Y. Romin, V. Boyko, S. Fujisawa, E. Kelly, G. W. Lynch, G. Rogers, K. Manova, M. A. Moore

The paper identifies a novel hydrodynamic mechanism, cell-projection pumping, for cytoplasmic transfer between mammalian cells, supported by mathematical modeling and simulations.

Biophysical Journal · Mar 1, 2020Peer-reviewedCell Biology

Increased cell size, structural complexity and migration of cancer cells acquiring fibroblast organelles by cell-projection pumping

H. Zoellner, B. Chami, E. Kelly, M. A. Moore

This paper shows cancer cells acquire fibroblast organelles via cell-projection pumping, leading to increased size, complexity, and migration, which may contribute to cancer progression.

bioRxiv · Sep 16, 2019Cancer Biology

Fentanyl depression of respiration: comparison with heroin and morphine

R. Hill, R. Santhakumar, W. L. Dewey, E. Kelly, G. Henderson

This study compares how fentanyl, heroin, and morphine depress respiration in mice, finding that fentanyl's rapid onset, increased muscle stiffness, and reduced naloxone reversal contribute to its higher lethality.

bioRxiv · Jun 6, 2019Pharmacology & Toxicology