T:B cell cooperation in ectopic lymphoid follicles propagates CNS autoimmunity
A. Kolz, I. J. Bauer, C. de la Rosa, V. Kavaka, A. S. Thomann, R. Schmitz, M. Kerschensteiner, E. Beltran, N. Kawakami, A. Peters
This study shows that T:B cell cooperation in meningeal ectopic lymphoid follicles (eLFs) promotes CNS autoimmunity by reactivating autoreactive T cells and supporting B cell clonal expansion.
bioRxiv · Jun 1, 2023Immunology