A. Peters

The integrated stress response/eIF2α pathway controls cytokine production in tissue-resident memory CD4+ T cells

This study shows that the ISR/eIF2α pathway regulates cytokine mRNA translation in Trm cells, limiting their activity in homeostasis but enabling rapid response during inflammation or autoimmunity.

T:B cell cooperation in ectopic lymphoid follicles propagates CNS autoimmunity

This study shows that T:B cell cooperation in meningeal ectopic lymphoid follicles (eLFs) promotes CNS autoimmunity by reactivating autoreactive T cells and supporting B cell clonal expansion.

Memory Th1 cells modulate heterologous diseases through innate function

This study identifies memory Th1 cells that can respond rapidly to unrelated pathogens or diseases through TCR-independent IFN-γ production, influencing susceptibility to heterologous challenges.

Demographic impacts of low- and high-intensity fire in a riparian savanna bird: implications for ecological fire management

This study examines the demographic effects of low- and high-intensity fires on a bird species in riparian habitats, finding that both fire types reduce population density but through different mechanisms.

Unexpected long-term retention of subcutaneous beeswax implants and additional notes on dose and composition from four testosterone implant studies

GM-CSF drives immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12

The paper identifies GM-CSF-producing T cells that drive glomerulonephritis by licensing monocyte-derived cells to produce MMP12, leading to renal tissue damage.

Cooperative breeding and the emergence of multilevel societies in birds

The paper investigates the prevalence of multilevel societies in cooperatively breeding birds, finding structured social hierarchies in superb fairy-wrens.

T cells modulate the microglial response to brain ischemia

This study shows engineered T cells overexpressing IL-10 alter microglial gene expression to a pro-regenerative profile after stroke, highlighting T cell-microglia interactions in neuroinflammation.

Arrhythmic gut microbiome signatures for risk profiling of Type-2 Diabetes

The paper identifies arrhythmic gut microbiome signatures associated with Type-2 Diabetes risk and validates them in a separate cohort.

Selection shapes synonymous stop codon use in mammals

The paper estimates that 57% of mammalian genes are under purifying selection for stop codon preference, with UGA codons being more conserved and associated with specific gene characteristics.