MyoD-Cre driven alterations in K-Ras and p53 lead to a mouse model with histological and molecular characteristics of human rhabdomyosarcoma with direct translational applications
K. Nakahata, B. W. Simons, E. Pozzo, R. Shuck, L. Kurenbekova, C. Coarfa, T. D. Patel, J. T. Yustein
This paper develops a genetically engineered mouse model of rhabdomyosarcoma with molecular features similar to human RMS, providing pre-clinical tools for therapy evaluation.
bioRxiv · Jun 15, 2021 · PreprintCancer Biology