Author

R. Suckling

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Korona· 1 shared C. Chillakuri· 1 shared L. Holt· 1 shared P. Handford· 1 shared P. Whiteman· 1 shared S. Lea· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

B. Korona

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1 paper

Recent·Most cited

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands

R. Suckling, B. Korona, P. Whiteman, C. Chillakuri, L. Holt, P. Handford, S. Lea

The paper presents structures of Notch ligands and functional assays showing that membrane recognition via the C2 domain is critical for Notch signaling, with mutations affecting this process leading to disease.

bioRxiv · Jan 18, 2017Biochemistry