Author

Rachel E.M. Schaefer

Veterans Health Administration

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alyse W. StaleyiD· 1 shared Arianne L. TheissiD· 1 shared Calen A. SteineriD· 1 shared Caroline H. T. HalliD· 1 shared David J. OrlickyiD· 1 shared Faiz Minhajuddin· 1 shared Geetha BhagavatulaiD· 1 shared Ian M. CartwrightiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alyse W. StaleyORCID

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1 paper

Recent·Most cited

Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner

Rosemary C. Callahan, Jillian Curry, Geetha Bhagavatula, Alyse W. Staley, Rachel E.M. Schaefer, Faiz Minhajuddin, Liheng Zhou, Rane M. Neuhart, Shaikh Muhammad Atif, David J. Orlicky, Ian M. Cartwright, Mark E. Gerich, Calen A. Steiner, Arianne L. Theiss, Caroline H. T. Hall, , Joseph C. Onyiah

This study shows that epithelial HO-1 promotes colonic tumorigenesis in chronic inflammation by increasing iron availability and oxidative stress, while protecting against acute heme toxicity.

JCI Insight · Dec 17, 2025Peer-reviewedCancer Biology