Author

Randy Clevenger

National Institutes of Health

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Audrey C. Noguchi· 1 shared Chengyu LiuiD· 1 shared Danielle SpringeriD· 1 shared Fan ZhangiD· 1 shared Hiroko Ishiwata-EndoiD· 1 shared Hong San· 1 shared Jiro KatoiD· 1 shared Joel MossiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Audrey C. Noguchi

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1 paper

Recent·Most cited

A PARP inhibitor, rucaparib, improves cardiac dysfunction in ADP-ribose-acceptor hydrolase 3 (Arh3) deficiency

Sachiko Yamashita, Xiangning Bu, Hiroko Ishiwata-Endo, Jiro Kato, Danielle Springer, Audrey C. Noguchi, Morteza Peiravi, Chengyu Liu, Fan Zhang, Zu‐Xi Yu, Randy Clevenger, Karen J. Keeran, Hong San, Martin J. Lizak, Joel Moss

This study shows that ARH3 deficiency causes cardiac dysfunction and that rucaparib, a PARP inhibitor, improves cardiac contractility and reduces infarct size in ARH3-deficient mice.

bioRxiv · Feb 7, 2023 · PreprintMolecular Biology