Author

Xiangning Bu

George Washington University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ananya Gottumukkala· 1 shared Audrey C. Noguchi· 1 shared Chengyu LiuiD· 1 shared Christine B. Teal· 1 shared Danielle SpringeriD· 1 shared Fan ZhangiD· 1 shared Hiroko Ishiwata-EndoiD· 1 shared Hong San· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Ananya Gottumukkala

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2 papers

Recent·Most cited

Cell crowding activates pro-invasive mechanotransduction pathway in high-grade DCIS via TRPV4 inhibition and cell volume reduction

Xiangning Bu, Nathanael Ashby, Teresa Vitali, Sulgi Lee, Ananya Gottumukkala, Kangsun Yun, Sana O. Tabbara, Patricia S. Latham, Christine B. Teal, Inhee Chung

This study shows cell crowding promotes invasion in high-grade DCIS by reducing cell volume through TRPV4 inhibition and mechanotransduction.

eLife · Sep 26, 2024Peer-reviewedCell Biology

A PARP inhibitor, rucaparib, improves cardiac dysfunction in ADP-ribose-acceptor hydrolase 3 (Arh3) deficiency

Sachiko Yamashita, Xiangning Bu, Hiroko Ishiwata-Endo, Jiro Kato, Danielle Springer, Audrey C. Noguchi, Morteza Peiravi, Chengyu Liu, Fan Zhang, Zu‐Xi Yu, Randy Clevenger, Karen J. Keeran, Hong San, Martin J. Lizak, Joel Moss

This study shows that ARH3 deficiency causes cardiac dysfunction and that rucaparib, a PARP inhibitor, improves cardiac contractility and reduces infarct size in ARH3-deficient mice.

bioRxiv · Feb 7, 2023 · PreprintMolecular Biology