Loss of the high-affinity vacuolar Ca2+ pump Pmc1p confers echinocandin tolerance in Candida albicans through enhancing calcineurin-based responses.
Justin B. Gregor, Ravinder Kumar, Christian A. DeJarnette, Glen E. Palmer
This study shows that loss of Pmc1p in Candida albicans increases tolerance to echinocandins by enhancing calcineurin signaling.
bioRxiv · Aug 28, 2026 · PreprintMicrobiology