Christian A. DeJarnette

This study shows that loss of Pmc1p in Candida albicans increases tolerance to echinocandins by enhancing calcineurin signaling.

This study identifies over 20 drugs that induce echinocandin tolerance in Candida albicans, revealing their mechanism involves multiple signaling pathways and transcriptional changes.

This study shows that aripiprazole, an atypical antipsychotic, worsens outcomes of disseminated Candida albicans infections in mice but has minimal effects on fungal growth or gene expression.