Author

Rema Iyer

Sanford Burnham Prebys Medical Discovery Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Aditi Pedgaonkar· 1 shared Alice SoragniiD· 1 shared Anagha J. DeshpandeiD· 1 shared Aniruddha J. DeshpandeiD· 1 shared Darren FinlayiD· 1 shared Gerard L. BrieniD· 1 shared Hiromi I Wetterstein· 1 shared Kristiina VuoriiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aditi Pedgaonkar

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1 paper

Recent·Most cited

Cancer BiologyThe EMBO JournalPeer-reviewedAug 13, 2025

SUMO2 Inhibition Reverses Aberrant Epigenetic Rewiring Driven by Synovial Sarcoma Fusion Oncoproteins and Impairs Sarcomagenesis

Rema Iyer, Anagha J. Deshpande, Aditi Pedgaonkar…·Aniruddha J. Deshpande

This study identifies SUMO2 as a selective vulnerability in synovial sarcoma, showing that SUMO2 inhibition reverses SS18-SSX-driven gene expression and impairs tumor growth.

6 citations

humanbulk RNA-seq