Immune checkpoint inhibitors amplify type 2 immune mediated repair bypro-regenerative scaffolds
Jordan T. Garcia, Anna Ruta, Fei Yu, Joscelyn C. Mejías, Alexis N. Peña, Natalie Rutkowski, Elise F. Gray-Gaillard, Constance Dubois, Christopher Cherry, Maria Browne, Katlin B. Stivers, David R. Maestas, Kavita Krishnan, Alexander T.F. Bell, Elana Judith Fertig, , Jennifer H. Elisseeff
This study shows immune checkpoint inhibitors enhance type 2 immunity and regeneration in ECM-treated wounds by promoting Treg/TH2 plasticity and pro-regenerative macrophages.
bioRxiv · Feb 3, 2026 · PreprintBioengineering