Mechanically Compliant, Precision-Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration
Ian D. Dryg, Le Zhen, Rebecca Darrow, Savannah Lawton, Lars Crawford, Robert Robinson, Steve I. Perlmutter, James D. Bryers, Buddy D. Ratner
Brain-stiffness-matched pHEMA/GMA hydrogel scaffolds with 40 µm interconnected pores reduced astrocyte encapsulation and iNOS+ macrophage fraction versus stiff solid rods after 4 weeks in rat brain.
Advanced Healthcare Materials · Aug 3, 2026Peer-reviewedBioengineering✦ In-depth digest