Author

Ryan E. Hoang

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Audrey V. ParentiD· 2 shared Aarti Anand· 1 shared Alena BoosiD· 1 shared Andrew Kelvin SewelliD· 1 shared Austin CheniD· 1 shared Daniel TraumiD· 1 shared Edwin BremeriD· 1 shared Fabian J. Theis· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Audrey V. ParentORCID

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Author profile →

2 papers

Recent·Most cited

MAFA drives pancreatic islet maturation through coordination of cell growth, metabolic maturation, and resilience to stress.

Veronica A. Cochrane, Michael Sterr, Marianne Aniag, Sara Jiménez, Madeline S. Wang, Ying Liu, Alena Boos, Juliane Merl‐Pham, Aarti Anand, Ryan E. Hoang, Rachita Gupta, Heiko Lickert, Tiago C. Alves, Jeeyeon Cha, Roland Stein, , Matthias Hebrok

This study shows that MAFA promotes pancreatic islet maturation by enhancing cell growth, metabolic function, and stress resilience in stem cell-derived islets.

bioRxiv · Sep 30, 2026 · PreprintCell Biology

A universal platform for simultaneous TCRα/β removal enables safer and more potent TCR therapies and autoimmune modeling

Giorgia Zanetti, Mateusz Legut, Austin Chen, Farshid Fathi, Nathan Suek, Nato Teteloshvili, Hao Wei Li, Xiaolan Ding, Daniel Traum, Klaus H. Kaestner, Ryan E. Hoang, Edwin Bremer, Andrew Kelvin Sewell, Audrey V. Parent, Rémi J. Creusot, , Mohsen Khosravi Maharlooei

This paper presents a CRISPR-based platform that removes endogenous TCRα/β chains to enhance transgenic TCR function and safety in T-cell therapies and autoimmune modeling.

bioRxiv · Feb 20, 2026 · PreprintImmunology