Author

Ryan Lancione

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:multiome· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Allen WangiD· 3 shared Justin BuchananiD· 3 shared Kelsey DangiD· 3 shared Bing ReniD· 2 shared Chanrung SengiD· 2 shared Daofeng LiiD· 2 shared Qian Yang· 2 shared Ting WangiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenomics

Allen WangORCID

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Author profile →

3 papers

Recent·Most cited

Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina

Ying Yuan, Pooja Biswas, Nathan R. Zemke, Kelsey Dang, Yue Wu, Matteo D’Antonio, Yang Xie, Qian Yang, Keyi Dong, Pik Ki Lau, Daofeng Li, Chanrung Seng, Weronika M. Bartosik, Justin Buchanan, Lin Lin, , Bing Ren

The paper performs single-cell multiomics analysis of the human retina to identify regulatory elements and develop predictors for non-coding risk variants.

Science Advances · Jul 23, 2026Peer-reviewedGenomics

Loss of tight junction protein claudin 18 uncovers alveolar epithelial stem cell plasticity and emergence of non-fibrogenic transitional progenitors

Alessandra Castaldi, J. Chin, B Ma, Max W. Chang, K. Samimi, A. Allen, W Pinson-Rose, Jonathan Castillo, Peyman Zamani, M Xie, Nataly Arias, Kayvon Solaimanpour, Y Liu, Hua Min Shen, BT Scott, , Zea Borok

The paper identifies regeneration-associated transitional progenitors (RATPs) in Cldn18 knockout mice, showing they are less fibrogenic and contribute to lung repair rather than fibrosis.

bioRxiv · Oct 1, 2025 · PreprintCell Biology

Single cell multiomics reveals drivers of metabolic dysfunction-associated steatohepatitis

Weston S. Elison, Lei Chang, Yang Xie, Charlene Miciano, Qian Yang, Hannah M Mummey, Ryan Lancione, Sierra Corban, Sadatsugu Sakane, Jacinta D. Lucero, Sainath Mamde, Hyun Sik Kim, Matthew J Kim, Rebecca L. Melton, Luca Tucciarone, , Kyle J. Gaulton

This study uses single-cell multi-omics to identify cell type-specific regulatory networks and novel therapeutic targets in MASLD.

medRxiv · May 9, 2025 · PreprintGenetic & Genomic Medicine