Author

K. Samimi

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:human· 4 Assay:imaging· 3 Research Focus:metabolism & bioenergetics· 3 Approach:deep learning· 2 Organism:mouse· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

M. C. Skala· 4 shared E. C. Guzman· 2 shared J. Riendeau· 2 shared A. A. Gillette· 1 shared A. Allen· 1 shared A. Houghtaling· 1 shared A. Huttenlocher· 1 shared A. J. Walsh· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersBioengineering

M. C. Skala

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Loss of tight junction protein claudin 18 uncovers alveolar epithelial stem cell plasticity and emergence of non-fibrogenic transitional progenitors

Alessandra Castaldi, J. Chin, B Ma, Max W. Chang, K. Samimi, A. Allen, W Pinson-Rose, Jonathan Castillo, Peyman Zamani, M Xie, Nataly Arias, Kayvon Solaimanpour, Y Liu, Hua Min Shen, BT Scott, , Zea Borok

The paper identifies regeneration-associated transitional progenitors (RATPs) in Cldn18 knockout mice, showing they are less fibrogenic and contribute to lung repair rather than fibrosis.

bioRxiv · Oct 1, 2025 · PreprintCell Biology

Autofluorescence lifetime flow cytometry with time-correlated single photon counting

K. Samimi, O. Pasachhe, E. C. Guzman, J. Riendeau, A. A. Gillette, D. L. Pham, K. J. Wiech, D. L. Moore, M. C. Skala

This paper introduces a TCSPC-based flow cytometer for real-time single-cell autofluorescence lifetime analysis, demonstrating viability and sensitivity to metabolic changes in various cell types.

bioRxiv · May 15, 2024Cell Biology

Optical coherence tomography of human fetal membrane sub-layers during dynamic loading

K. Samimi, E. Contreras Guzman, M. Wu, L. Carlson, H. Feltovich, T. J. Hall, K. M. Myers, M. L. Oyen, M. C. Skala

This study uses optical coherence tomography to analyze the mechanical properties of human fetal membranes under dynamic loading, identifying the amnion as the load-bearing layer and location-dependent thickness variations.

bioRxiv · Mar 9, 2023Biophysics

Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array

K. Samimi, D. E. Desa, W. Lin, K. Weiss, J. Li, J. Huisken, V. Miskolci, A. Huttenlocher, J. V. Chacko, A. Velten, J. D. Rogers, K. W. Eliceiri, M. C. Skala

This paper introduces a light sheet FLIM system using SPAD arrays for fast, label-free single-cell NAD(P)H autofluorescence imaging in live cells and organisms.

bioRxiv · Feb 1, 2023Bioengineering

Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype

R. L. Schmitz, K. E. Tweed, P. Rehani, K. Samimi, J. Riendeau, I. Jones, E. M. Maly, E. C. Guzman, M. H. Forsberg, A. Shahi, C. M. Capitini, A. J. Walsh, M. C. Skala

This paper uses optical metabolic imaging to classify human lymphocyte activation and subtype with high accuracy using autofluorescence lifetime parameters.

bioRxiv · Jan 23, 2023 · PreprintBioengineering

Label-free imaging for quality control of cardiomyocyte differentiation

T. Qian, T. Heaster, A. Houghtaling, K. Sun, K. Samimi, M. Skala

The paper develops a label-free imaging method to predict cardiomyocyte differentiation efficiency from hPSCs using autofluorescence and multivariate models.

bioRxiv · Jun 1, 2021Bioengineering