Rete Ridge Topography as a Determinant of Epidermal Stem Cell Identity: Implications for Skin Aging
Rui Fang, Ryoko Hamaguchi, S. Xu, Wonhye Lee, Kristina A. Todorova, Stefano Sol, Xunwei Wu, Mindy Nguyen, Jacob Shi, Alvaro C. Laga, Seung‐Schik Yoo, George Murphy, Anna Mandinova, Christine Guo Lian
This study shows that the concave topography of rete ridges influences epidermal stem cell differentiation and function, with changes in topography contributing to skin aging.
bioRxiv · Apr 10, 2026 · PreprintCell Biology