Author

S. A. Killackey

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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D. Arnoult· 1 shared D. J. Philpott· 1 shared L. Schweizer· 1 shared P. Y. Bi· 1 shared S. E. Girardin· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

D. Arnoult

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1 paper

Recent·Most cited

Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

P. Y. Bi, S. A. Killackey, L. Schweizer, D. Arnoult, D. J. Philpott, S. E. Girardin

This study identifies mitochondrial protein import stress (MPIS) as the trigger for the DELE1-HRI pathway and shows HtrA2 mediates DELE1 cleavage into distinct forms under stress.

bioRxiv · Feb 26, 2023 · PreprintCell Biology