Author

L. Schweizer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

M. Mann· 2 shared A. Metousis· 1 shared A. Mund· 1 shared A. Raue· 1 shared B. Shen· 1 shared C. Blume· 1 shared C. Lavarino· 1 shared C. Mawrin· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPathology

M. Mann

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

P. Y. Bi, S. A. Killackey, L. Schweizer, D. Arnoult, D. J. Philpott, S. E. Girardin

This study identifies mitochondrial protein import stress (MPIS) as the trigger for the DELE1-HRI pathway and shows HtrA2 mediates DELE1 cleavage into distinct forms under stress.

bioRxiv · Feb 26, 2023 · PreprintCell Biology

A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics

T. M. Nordmann, L. Schweizer, A. Metousis, M. Thielert, E. Rodriguez, L. M. Rahbek-Gjerdrum, P.-C. Stadler, M. Bzorek, A. Mund, F. A. Rosenberger, M. Mann

This paper introduces a workflow for using membrane glass slides in histology and spatial proteomics, improving compatibility with automated staining and preserving antigen retrieval.

bioRxiv · Feb 20, 2023Pathology

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial ependymoma

P. Sievers, S. C. Henneken, C. Blume, M. Sill, D. Schrimpf, D. Stichel, K. Okonechnikov, D. E. Reuss, J. Benzel, K. Maass, M. Kool, D. Sturm, P. Kohlhof-Meinecke, O. Cruz, M. Mariona Sunol, , Z

The paper identifies a novel subset of supratentorial ependymomas in children characterized by recurrent PLAGL1 fusions and distinct molecular features.

bioRxiv · Apr 23, 2021 · PreprintCancer Biology

Single-cell immune profiling with TCR clonotype barcoding identifies biomarker signatures that predict response to immune checkpoint blockade

D. Lee, R. Fulton, M. Manne, L. Schweizer, A. Raue

The paper identifies a gene expression signature predicting response to immune checkpoint blockade using TCR clonotype barcoding in single-cell data from a small cohort, validated in larger studies.

bioRxiv · Apr 13, 2021 · PreprintImmunology

A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

J. B. Mueller-Reif, F. M. Hansen, L. Schweizer, P. V. Treit, P. E. Geyer, M. Mann

A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns, reducing production time by 40 to 800 times.

bioRxiv · Feb 26, 2021Biochemistry

High throughput functional screening for next generation cancer immunotherapy using droplet-based microfluidics

Y. Wang, R. Jin, B. Shen, N. Li, H. Zhou, W. Wang, Y. Zhao, M. Huang, P. Fang, S. Wang, P. Mary, R. Wang, P. Ma, R. Li, Y. Cao, , h. Zhang

This paper develops a droplet-based microfluidics platform for high-throughput functional antibody screening, identifying potent cancer immunotherapeutics like CD40 agonists and anti-Her2/anti-CD3 bispecific antibodies.

bioRxiv · Nov 25, 2020Cancer Biology