Author

S. A. Zwarthoff

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kuipers· 1 shared C. J. C. de Haas· 1 shared D. Ricklin· 1 shared D. Ugurlar· 1 shared F. J. Beurskens· 1 shared G. Vidarsson· 1 shared J. Preiner· 1 shared J. Schuurman· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Kuipers

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1 paper

Recent·Most cited

ImmunologybioRxivFeb 8, 2021

C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases

S. A. Zwarthoff, K. Widmer, A. Kuipers…·S. H. M. Rooijakkers

This study shows that C1r2s2 proteases stabilize C1q binding to surface-bound IgG, with subclass-specific effects and improved phagocytosis with hexamer-enhanced IgGs.

DOI 10.1073/pnas.2102787118

humanproteomics