Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes
K. Yu, A. Basu, C. Yau, D. M. Wolf, H. Goodarzi, S. Bandyopadhyay, J. E. Korkola, G. L. Hirst, S. Asare, I-SPY 2 TRIAL, A. Demichele, N. Hylton, D. Yee, L. Esserman, L. van 't Veer, M. Sirota
This study uses computational drug repositioning to identify agents that can sensitize drug-resistant breast tumors, finding fulvestrant effective across multiple treatment and receptor subtypes.
bioRxiv · Mar 30, 2023Cell Biology