Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments
H. Demirci, S. Popovic, C. Dittmayer, D. E. Yilmaz, I. A. El-Shimy, M. Mülleder, C. Hinze, P. B. Persson, K. Mutig, S. Bachmann
This study compares nephrotoxicity of cyclosporine and tacrolimus in rat kidneys using multiomics and histopathology, revealing distinct damage patterns in glomerular and tubular compartments.
bioRxiv · Apr 5, 2023Pathology