Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses
L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer
This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.
bioRxiv · Sep 27, 2021Cancer Biology