Human TRMT2A methylates tRNA and contributes to translation fidelity
M. Witzenberger, S. Burczyk, D. Settele, W. Mayer, L. M. Welp, M. Heiss, M. Wagner, T. Monecke, R. Janowski, T. Carell, H. Urlaub, S. M. Hauck, A. Voigt, D. Niessing
This study identifies TRMT2A as a tRNA methyltransferase that contributes to translation fidelity by modifying tRNA with m5U at position 54.
bioRxiv · Dec 28, 2022Biochemistry