Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications
M. Lopes, T. Duarte, M. J. Teles, L. Mosteo, S. Chacim, E. Aguiar, J. Pereira-Reis, M. Oliveira, A. M. N. Silva, N. Goncalves, G. Martins, I. Kong, M. Zethoven, S. Vervoort, S. Martins, , D. Duarte
The paper investigates iron metabolism in AML, finding that AML causes iron redistribution through erythroblast loss, leading to high TSAT and improved survival.
bioRxiv · Oct 26, 2020Cancer Biology