Author

S. E. Leininger

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

E. P. O'Brien· 2 shared C. Deutsch· 1 shared D. A. Nissley· 1 shared F. Trovato· 1 shared J. Rodriguez· 1 shared M. S. Li· 1 shared Q. V. Vu· 1 shared Y. Jiang· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

E. P. O'Brien

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2 papers

Recent·Most cited

Ribosome elongation kinetics of consecutively charged residues are coupled to electrostatic force

S. E. Leininger, J. Rodriguez, Q. V. Vu, Y. Jiang, M. S. Li, C. Deutsch, E. P. O'Brien

The paper shows charged residues affect ribosome elongation speed through mechanochemical forces, supported by simulations and experimental data.

bioRxiv · Aug 4, 2021Biophysics

Domain topology, stability, and translation speed determine mechanical force generation on the ribosome

S. E. Leininger, F. Trovato, D. A. Nissley, E. P. O'Brien

This study shows that mechanical forces on ribosomes during translation depend on domain stability, topology, and translation speed, with implications for protein structure and evolution.

bioRxiv · Dec 7, 2018Biophysics