Author

S. E. Schaus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. G. Chin· 2 shared U. Hansen· 2 shared C. Ruse· 1 shared C. S. Pedamallu· 1 shared H. Shin· 1 shared J. L. S. Willoughby· 1 shared J. Lee· 1 shared J. Shah· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

H. G. Chin

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2 papers

Recent·Most cited

Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

J. L. S. Willoughby, K. George, M. P. Roberto, H. G. Chin, P. Stoiber, H. Shin, C. S. Pedamallu, S. E. Schaus, K. Fitzgerald, J. Shah, U. Hansen

This study shows that inhibiting LSF with FQI1 or siRNA causes mitotic delays and cell death in HeLa cells, supporting LSF as a cancer therapeutic target.

bioRxiv · Jan 26, 2020Cancer Biology

Transcription factor LSF facilitiates lysine methylation of α-tubulin by microtubule-associated SET8

H. G. Chin, P. O. Esteve, C. Ruse, J. Lee, S. E. Schaus, S. Pradhan, U. Hansen

The paper identifies LSF as a facilitator of SET8-mediated α-tubulin methylation, revealing a novel role for these proteins in cytoskeletal modification during mitosis.

bioRxiv · Jun 10, 2019Biochemistry