Force Field Dependent DNA Breathing Dynamics: A Case Study of Hoogsteen Base Pairing in A6-DNA
S. E. Stone, D. Ray, I. Andricioaei
This paper investigates how different force field models affect the WC to HG base pair transition in DNA, finding that enthalpic stabilization and entropy balance determine conformational stability.
bioRxiv · May 4, 2022Biophysics