IL-27 receptor signaling regulated stress myelopoiesis drives Abdominal Aortic Aneurysm development
I. Peshkova, T. Aghayev, A. Fatkhullina, P. Makhov, S. Eguchi, Y. F. Tan, A. Kossenkov, S. Sykes, E. Koltsova
This study shows that IL-27 receptor signaling in hematopoietic stem cells drives abdominal aortic aneurysm development by promoting myeloid cell accumulation.
bioRxiv · Feb 20, 2019Immunology