The nuclear speckles protein SRRM2 is a new therapeutic target molecule on the surface of cancer cells
M. Kellner, J. Hoermann, S. Fackler, H. Yuanyu, L. Lin, I. Ilik, T. Aktas, R. Feederle, S. M. Hauck, O. Gires, K. Gaertner, L. Lietao, R. Zeidler
The paper identifies SRRM2 as a surface-exposed cancer target and shows its utility in CAR-T cell therapy.
bioRxiv · Apr 26, 2024 · PreprintCancer Biology