An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury
S. Fleischer, T. R. Nash, M. A. Tamargo, R. I. Lock, G. Venturini, M. Morsink, V. Li, M. J. Lamberti, P. L. Graney, M. Liberman, Y. Kim, R. Z. Zhuang, J. Whitehead, R. A. Friedman, R. SONI, , G. Vunjak-Novakovic
This study uses engineered human cardiac tissues to show how SLE autoantibodies affect myocardial injury through distinct binding patterns and functional effects on cardiac cells.
bioRxiv · Mar 7, 2024Bioengineering