R. Soni

An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

This study uses engineered human cardiac tissues to show how SLE autoantibodies affect myocardial injury through distinct binding patterns and functional effects on cardiac cells.

Replication stress in activated human NK cells induces sensitivity to apoptosis

This study shows that replication stress in activated human NK cells increases apoptosis and impairs function, linking helicase deficiency to NK cell deficiency.

Automatic Abdominal Multi Organ Segmentationusing Residual UNet

This paper develops a residual UNet model for abdominal multi-organ segmentation using CT and MRI scans, achieving high Dice scores in held-out tests.

Automatic Whole Body FDG PET/CT Lesion Segmentation using Residual UNet and Adaptive Ensemble

The paper develops a deep learning method using residual UNET and adaptive ensemble for automated FDG PET/CT lesion segmentation, achieving a dice score of 0.5541 on a test dataset.

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

The paper identifies the CD58:CD2 axis as co-regulated with PD-L1 via CMTM6 and shows its role in anti-tumor immunity, proposing therapeutic strategies to enhance immunotherapy.

STK25 inhibits PKA signaling by phosphorylating PRKAR1A

This study identifies STK25 as a kinase that phosphorylates PRKAR1A, inhibiting PKA signaling and reducing myocardial contractility in response to beta adrenergic stimulation.

Vaping Perpetuates Cardiac Electrical Instability

This study shows that vaping with flavored e-liquids increases cardiac electrical instability in vitro and in vivo, suggesting potential cardiac toxicity.