A system-wide approach to monitor responses to synergistic BRAF and EGFR inhibition in colorectal cancer cells
A. Ressa, E. Bosdriesz, J. de Ligt, S. Mainardi, G. Maddalo, A. Prahallad, M. Jager, L. de la Fonteijne, M. Fitzpatrick, S. Groten, A. F. M. Altelaar, R. R. Bernards, E. Cuppen, L. Wessels, A. J. R. Heck
The paper investigates molecular responses to BRAF and EGFR inhibition in colorectal cancer cells, revealing metabolic shifts and MAPK pathway reactivation.
bioRxiv · Sep 27, 2017Cancer Biology