Author

M. Fitzpatrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Amini· 1 shared A. Baranski· 1 shared A. Delmastro· 1 shared A. F. M. Altelaar· 1 shared A. Folgori· 1 shared A. J. C. Steyn· 1 shared A. J. R. Heck· 1 shared A. Pollard· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Amini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Relationships between climate and phylogenetic community structure of fossil pollen assemblages are not constant during the last deglaciation

K. Pradhan, D. Nieto-Lugilde, M. Fitzpatrick

This study examines the stability of climate-phylogenetic community structure relationships in fossil pollen assemblages over the last 21,000 years, finding unstable slopes but stable intercepts.

bioRxiv · Oct 7, 2020Ecology

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

E. F. McCaffrey, M. Donato, L. Keren, Z. Chen, M. Fitzpatrick, V. Jojic, A. Delmastro, N. F. Greenwald, A. Baranski, W. Graf, M. Bosse, P. K. Ramdial, E. Forgo, D. Van Valen, M. van de Rijn, , M. Angelo

This study uses multiplexed imaging and transcriptomics to identify immunosuppressive features in TB granulomas and blood, linking local and systemic immune responses.

bioRxiv · Jun 8, 2020 · PreprintImmunology

Activation of MAIT cells plays a critical role in viral vector vaccine immunogenicity

N. Provine, A. Amini, L. Garner, C. Dold, C. Hutchings, M. FitzPatrick, L. Silva Reyes, S. Chinnakannan, B. Oguti, M. Raymond, S. Capone, A. Folgori, C. Rollier, E. Barnes, A. Pollard, P. Klenerman

This study shows that MAIT cell activation is essential for the immunogenicity of adenovirus vector vaccines, as it drives HCV-specific CD8 T cell responses.

bioRxiv · Jun 13, 2019 · PreprintImmunology

A system-wide approach to monitor responses to synergistic BRAF and EGFR inhibition in colorectal cancer cells

A. Ressa, E. Bosdriesz, J. de Ligt, S. Mainardi, G. Maddalo, A. Prahallad, M. Jager, L. de la Fonteijne, M. Fitzpatrick, S. Groten, A. F. M. Altelaar, R. R. Bernards, E. Cuppen, L. Wessels, A. J. R. Heck

The paper investigates molecular responses to BRAF and EGFR inhibition in colorectal cancer cells, revealing metabolic shifts and MAPK pathway reactivation.

bioRxiv · Sep 27, 2017Cancer Biology