Signatures of copy number alterations in human cancer
C. D. Steele, A. Abbasi, A. S. M. Islam, A. Khandekar, K. Haase, S. Hames, M. Tarabichi, T. Lesluyes, A. M. Flanagan, F. Mertens, P. Van Loo, L. B. Alexandrov, N. Pillay
This paper identifies 19 copy number signatures in 9,873 cancers, explaining 93% of TCGA samples, and reveals diverse mechanisms underlying copy number alterations in human cancer.
bioRxiv · Apr 30, 2021Cancer Biology