The thymic microenvironment gradually modulates the phenotype of thymus-homing peripheral conventional dendritic cells
S. Herppich, M. Beckstette, J. Huehn
This study shows that peripheral conventional dendritic cells (cDCs) can acquire thymic characteristics when exposed to thymic microenvironment in vitro, including immunomodulatory gene expression and Treg cell-inducing capacity.
bioRxiv · Aug 27, 2021Immunology