Folding and Persistence Time of Intramolecular G-Quadruplexes Transiently Embedded in a DNA duplex
P. L. T. Tran, M. Rieu, S. Hodeib, A. Joubert, J. Ouellet, P. Alberti, A. Bugaut, J.-F. Allemand, J.-B. Boule, V. Croquette
The paper measures G4 DNA folding and persistence in double-stranded DNA using a single-molecule assay, showing G4 stability varies by genomic location and is modulated by ligands.
bioRxiv · Jan 4, 2021Biophysics