Author

A. Joubert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:yeast· 1

Frequent Co-Authors

J.-B. Boule· 3 shared J.-F. Allemand· 2 shared M. Rieu· 2 shared P. L. T. Tran· 2 shared V. Croquette· 2 shared A. Bugaut· 1 shared A. Granzhan· 1 shared C. P. Gros· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

J.-B. Boule

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3 papers

Recent·Most cited

Strand-switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA

J. Valle-Orero, M. Rieu, P. L. T. Tran, A. Joubert, J.-F. Allemand, V. Croquette, J.-B. Boule

The paper develops a single-molecule assay to study Pif1 helicase resolving G-quadruplexes and reveals its strand-switching behavior affects G4 resolution efficiency.

bioRxiv · Jan 11, 2022Biophysics

Folding and Persistence Time of Intramolecular G-Quadruplexes Transiently Embedded in a DNA duplex

P. L. T. Tran, M. Rieu, S. Hodeib, A. Joubert, J. Ouellet, P. Alberti, A. Bugaut, J.-F. Allemand, J.-B. Boule, V. Croquette

The paper measures G4 DNA folding and persistence in double-stranded DNA using a single-molecule assay, showing G4 stability varies by genomic location and is modulated by ligands.

bioRxiv · Jan 4, 2021Biophysics

Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules

J. Mitteaux, P. Lejault, M. Pirrotta, F. Wojciechowski, A. Joubert, N. Desbois, C. P. Gros, R. H. E. Hudson, J.-B. Boule, A. Granzhan, D. Monchaud

The paper develops an in vitro assay to identify G4-disrupting molecules and characterizes a prototype small molecule that destabilizes G4-DNA.

bioRxiv · Nov 16, 2020Biophysics