Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease
C. E. Ellis, M. Mojibian, V. C. W. Fung, S. Skovso, E. McIver, S. ODwyer, T. D. Webber, M. J. S. Braam, S. Ida, N. Saber, T. J. Kieffer, M. K. Levings
This study shows that A2-CAR T cells can reject HLA-A2+ human islets in mice without causing graft-versus-host disease, enabling the study of islet rejection mechanisms.
bioRxiv · Feb 23, 2023Immunology